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10/04-30/05 Advances in Genome Technology and Bioinformatics. A comprehensive, four-week course in Genome Science that will integrate Bioinformatics with the latest laboratory techniques for genome sequencing, genome analysis, and high throughput gene expression (DNA microarrays). A distinguished faculty from major universities, bioinformatic centers, The Institute for Genomic Research and the Marine Biological Laboratory will train students including postdoctoral students, graduate students and established PI's. Online Application Form, (PDF) Deadline: June 30, 2005 07/20/05 We have performed Significance Analysis of Microarrays (SAM) on the Rat Studies, in addition to the previously reported t-Test datasets. Results can be accessed from the Data page. In addition, we have updated the Rat Expression Study Overview to include more detailed information on Consomic Animal generation, Experimental Design and Data Analysis. 11/06-11/04 Short Course on Gene Microarray Development and Analysis: Approaches to Heart, Lung, Blood and Sleep Disorders Organizers: John Quackenbush, Ph.D., and Norman Lee, Ph.D., The Institute for Genomic Research; Gary Churchill, Ph.D., Martin Ringwald, Ph.D., and John B. Macauley, Ph.D., The Jackson Laboratory. Offered twice each year, this workshop provides intensive hands-on training in the preparation and analysis of gene chips. The focus of this workshop is on microarray approaches to the study of heart, lung, and blood disease and associated sleep disorders. 10/05-31/04 Advances in Genome Biology and Bioinformatics. A comprehensive, four-week course in Genome Science that will integrate Bioinformatics with the latest laboratory techniques for genome sequencing, genome analysis, and high throughput gene expression (DNA microarrays). A distinguished faculty from major universities, bioinformatic centers, The Institute for Genomic Research and the Marine Biological Laboratory will train students including postdoctoral students, graduate students and established PI's. 05/07/2004 Accessing PGA data has become much easier with the addition of links which allow launching of TIGR MeV with data already loaded. Other recent changes to the site include the addition of tooltips to ease navigation of the data in the data browsing pages. Java WebStart stuff. 01/26/2004 The data section of the PGA site has been significantly updated. New data is available and all the data is presented in a new format. 10/30/2003 TREX PGA website has had a major update. We've added new data, etc. We've done all kinds of nifty-new stuff. Check out all the data! Keep in mind that the migration to the new page is an ongoing process, so all of our old data is not yet converted to the new format. Please see the old page if you can't find what you're looking for. 10/25/2003 TIGR Spotfinder TIGR Spotfinder was designed for the rapid, reproducible, and computer-aided analysis of microarray images and the quantification of gene expression.
MADAM (MicroArray DAta Manager) is a java-based application designed to load and retrieve microarray data to and from a database (also supplied with the software). MADAM provides data entry forms, data report forms and additional applications necessary to maintain microarray data for further analysis.
TIGR Microarray Data Analysis System (TIGR MIDAS) is a microarray data quality filtering and normalization tool that allows raw experimental data to be processed through various data normalizations, filters, and transformations via a user-designed analysis pipeline. Currently implemented normalization and data analysis algorithms include total-intensity normalization, Lowess (Locfit) normalization, flip-dye consistency checking, replicates analysis, intensity-dependent z-score filtering (slice analysis), etc. MIDAS is implemented by Java language and thus a platform-independent application.
TIGR MultiExperiment Viewer (MEV) is a Java application designed to allow the analysis of microarray data to identify patterns of gene expression and differentially expressed genes. Numerous normalization, clustering and distance algorithms have been implemented, along with a variety of graphical displays to best present the results.
10/02/2000 NHLBI Launches Genomic Applications Initiative - $37 Million Awarded in Initial Effort. 10/02/2000 TIGR is selected as an inaugural participant in national genomic research initiative.